Research

Here's most of my first-author work. For my complete publication list, see my Google Scholar.

* indicates equal contribution, # indicates corresponding author

• Tracking clonal evolution during treatment in ovarian cancer using cell-free DNA

  Marc J Williams#, ... Sohrab P. Shah#

  Nature, 2025

• Luminal breast epithelial cells of BRCA1 or BRCA2 mutation carriers and noncarriers harbor common breast cancer copy number alterations

  Marc J Williams*, Michael UJ Oliphant*, Vinci Au* ... Sohrab P. Shah, Joan S. Brugge and Samuel J Aparicio

  Nature Genetics, 2024

• Single-cell genomic variation induced by mutational processes in cancer

  Tyler Funnell*, Ciara H O'Flanagan*, Marc J Williams*#, ... Sohrab P. Shah# and Samuel J Aparicio

  Nature, 2022

• Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dn/ds ratios

  Marc J Williams#, Luiz Zapata, Benjamin Werner, Chris Barnes, Andrea Sottoriva, and Trevor A Graham#

  eLife, 2020

• Measuring Clonal Evolution in Cancer with Genomics

  Marc J Williams, Andrea Sottoriva, and Trevor A Graham.

  Annual Review of Genomics and Human Genetics, 2019

  Review Article

• Quantification of subclonal selection in cancer from bulk sequencing data

  Marc J Williams ... Chris P Barnes, Andrea Sottoriva, and Trevor A Graham.

  Nature Genetics, 2018

• Identification of neutral tumor evolution across cancer types

  Marc J Williams*, Benjamin Werner*, Chris P Barnes, Trevor A Graham, and Andrea Sottoriva.

  Nature Genetics, 2016